Low Concentration TOC Analyzer for Pharmaceutical Application
Scientific Product
Assistant Buniness Unit Manager : Miss. Rotsukon Chanseeharat
Tel : 081-988-2819
E-mail : rotsukon@pico.co.th
Admin
Tel : 02-939-5711 ext. 611
E-mail : scientific@pico.co.th
Description :
The continuous online TOC-Analyzer HT-110 is suitable for the measurement ot total organic carbons in Purified Water (PW), Water For Injection (WFI) and Highly Purified Water (HPW). The unit is operating according to USP 643. It is applicable for pharmaceutical and/or semiconductor manufacturing. The measuring principle is based on UV-Oxidation and measurement of the difference in conductivity. TOC concentration measurement (TOC concentration 500 ppbC or lower) is necessary to perform quality control according to GMP (Good Manufacturing Practice).
Characteristic :
- UV-Oxidation and conductivity determination: This method eliminates the need for reagents and carrier gases. It delivers an accurate measurement at low concentrations, like for instance in WFI (Water For Injection) areas and reduces the cost of operation at the same time.
- “Debubbler“ embedded: Bubbles in production systems often cause unstable readings in many instruments. The embedded “Debubbler“ eliminates the influence of air and guarantees a stable measurement.
- Optional external ON/OFF control of contact input terminals.
- Maintenance cycle: “ONLY ONCE PER YEAR“: Maintenance only consists of annual UV-lamp exchange and annual calibration.
- Conforms to: United States Pharmacopeia: USP <643>.
- Reference solutions for System Suitability Test (SST): 1,4 Benzoquinone and Sucrose
- Choice of 3 installation methods: Possible to install on a pole, wall or desktop.
Specification :
| Model | HT-110 | |
| Measurement method | Continuous UV-Oxidation and measurement of difference in conductivity | |
| Measuring range | 0 to 1000 ppb (Measuring range : 0 to 100 / 500 / 1000 ppb) |
|
| Display resolution | 0 to 100 ppb, 0.1 ppbC | |
| 0 to 500 ppb, 0.1 ppbC | ||
| 0 to 1000 ppb, 1 ppbC | ||
| Repeatability | Within ±2% of the full scale | |
| Transmission output | Number of outputs : 1 4 to 20 mA dc / 0 to 1 V dc (option): Input / Output isolated type Max. load resistance : (4 to 20 mA dc) 600 Ω. Min. load resistance ( 0 to 1 V dc) : 100 kΩ [with option selected]. Analog output range : Freely selectable within the measurement range Output contents : TOC concentration |
|
| Contact output | Number of outputs : 2* Alarm contact output (RLY1)
* Alarm contact output (RLY2)
|
|
| Sample conditions | Conductivity : < 10 µS/cm or lower (0 to 100 ppb: < 2 µS/cm or lower) Temperature : 5 to 99 °C Pressure : 0.03 MPa to 0.50 MPa Flow rate : 20 to 200 mL/min |
|
| Ambient environment | Temperature : 5 to 40 °C Humidity : 85% or lower |
|
| Display functions | LC with backlight Display content (TOC concentration, conductivity, temperature, alarm) |
|
| Structure | Protection : IP43 ; Paint color 5PB8/1; Epoxy coating (indoor-use panel installation type) |
|
| Power supply | AC 100 to 240 V ±10% 50/60 Hz 80 VA (max.) | |
| Mass | 13 kg | |
| Conforming standards | CE marking, FCC Part 15, USP <643> | |
